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BMCBI
2006
123views more  BMCBI 2006»
14 years 9 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
BMCBI
2007
131views more  BMCBI 2007»
14 years 9 months ago
ISHAPE: new rapid and accurate software for haplotyping
Background: We have developed a new haplotyping program based on the combination of an iterative multiallelic EM algorithm (IEM), bootstrap resampling and a pseudo Gibbs sampler. ...
Olivier Delaneau, Cédric Coulonges, Pierre-...
BMCBI
2011
14 years 3 months ago
PheMaDB: A solution for storage, retrieval, and analysis of high throughput phenotype data
Background: OmniLog™ phenotype microarrays (PMs) have the capability to measure and compare the growth responses of biological samples upon exposure to hundreds of growth condit...
Wenling E. Chang, Keri Sarver, Brandon W. Higgs, T...
NAR
2011
267views Computer Vision» more  NAR 2011»
14 years 3 months ago
EcoCyc: a comprehensive database of Escherichia coli biology
EcoCyc (http://EcoCyc.org) is a comprehensive model organism database for Escherichia coli K-12 MG1655. From the scientific literature, EcoCyc captures the functions of individual...
Ingrid M. Keseler, Julio Collado-Vides, Alberto Sa...