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» Comparative genome assembly
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92
Voted
BMCBI
2005
115views more  BMCBI 2005»
15 years 11 days ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
81
Voted
ICPR
2006
IEEE
16 years 1 months ago
A Hybrid, Recursive Algorithm for Clustering Expressed Sequence Tags in Chlamydomonas reinhardtii
We present an efficient, fully automated algorithm to assemble ESTs into full-length cDNA sequences that represent the complete coding regions of a gene. Our EST clustering algori...
Arthur Grossman, Charles Hauser, Hilary J. Holz, J...
108
Voted
BMCBI
2008
104views more  BMCBI 2008»
15 years 17 days ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
132
Voted
BMCBI
2008
131views more  BMCBI 2008»
15 years 17 days ago
CoCoNUT: an efficient system for the comparison and analysis of genomes
Background: Comparative genomics is the analysis and comparison of genomes from different species. This area of research is driven by the large number of sequenced genomes and hea...
Mohamed Ibrahim Abouelhoda, Stefan Kurtz, Enno Ohl...
126
Voted
BMCBI
2008
116views more  BMCBI 2008»
15 years 17 days ago
Clustering exact matches of pairwise sequence alignments by weighted linear regression
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
Alvaro J. González, Li Liao