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» Comparative genome assembly
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96
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BMCBI
2010
101views more  BMCBI 2010»
15 years 18 days ago
Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model
Background: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variat...
Zhengdong D. Zhang, Mark B. Gerstein
RECOMB
2009
Springer
15 years 7 months ago
Pseudo Boolean Programming for Partially Ordered Genomes
Comparing genomes of different species is a crucial problem in comparative genomics. Different measures have been proposed to compare two genomes: number of common intervals, num...
Sébastien Angibaud, Guillaume Fertin, Annel...
109
Voted
JCB
2008
111views more  JCB 2008»
14 years 12 months ago
Sorting Genomes with Centromeres by Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
Michal Ozery-Flato, Ron Shamir
110
Voted
BMCBI
2010
144views more  BMCBI 2010»
15 years 18 days ago
Graph-based clustering and characterization of repetitive sequences in next-generation sequencing data
Background: The investigation of plant genome structure and evolution requires comprehensive characterization of repetitive sequences that make up the majority of higher plant nuc...
Petr Novák, Pavel Neumann, Jirí Maca...
BMCBI
2010
128views more  BMCBI 2010»
15 years 18 days ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro