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103
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BMCBI
2010
183views more  BMCBI 2010»
15 years 18 days ago
SOPRA: Scaffolding algorithm for paired reads via statistical optimization
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
Adel Dayarian, Todd P. Michael, Anirvan M. Sengupt...
CSB
2005
IEEE
168views Bioinformatics» more  CSB 2005»
15 years 6 months ago
cis-Regulatory Element Prediction in Mammalian Genomes
The identification of cis-regulatory elements and modules is an important step in understanding the regulation of genes. We have developed a pipeline capable of running multiple m...
Asim S. Siddiqui, Gordon Robertson, Misha Bilenky,...
83
Voted
BMCBI
2005
80views more  BMCBI 2005»
15 years 12 days ago
Gene finding in the chicken genome
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...
113
Voted
IPPS
2005
IEEE
15 years 6 months ago
High-Performance Direct Pairwise Comparison of Large Genomic Sequences
Many applications in Comparative Genomics lend themselves to implementations that take advantage of common high-performance features in modern microprocessors. However, the common...
Christopher Mueller, Mehmet M. Dalkilic, Andrew Lu...
97
Voted
RECOMB
2005
Springer
16 years 24 days ago
Stability of Rearrangement Measures in the Comparison of Genome Sequences
We present data-analytic and statistical tools for studying rates of rearrangement of whole genomes and to assess the stability of these methods with changes in the level of resol...
David Sankoff, Matthew Mazowita