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» Comparative genome assembly
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OOPSLA
2010
Springer
14 years 11 months ago
Component adaptation and assembly using interface relations
Software’s expense owes partly to frequent reimplementation of similar functionality and partly to maintenance of patches, ports or components targeting evolving interfaces. Mor...
Stephen Kell
97
Voted
BMCBI
2010
126views more  BMCBI 2010»
15 years 20 days ago
Cgaln: fast and space-efficient whole-genome alignment
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
Ryuichiro Nakato, Osamu Gotoh
111
Voted
BMCBI
2010
101views more  BMCBI 2010»
15 years 20 days ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
105
Voted
JCDL
2010
ACM
199views Education» more  JCDL 2010»
15 years 5 months ago
Crowdsourcing the assembly of concept hierarchies
The“wisdom of crowds”is accomplishing tasks that are cumbersome for individuals yet cannot be fully automated by means of specialized computer algorithms. One such task is the...
Kai Eckert, Mathias Niepert, Christof Niemann, Cam...
109
Voted
NC
2008
15 years 14 days ago
How crystals that sense and respond to their environments could evolve
An enduring mystery in biology is how a physical entity simple enough to have arisen spontaneously could have evolved into the complex life seen on Earth today. Cairns-Smith has pr...
Rebecca Schulman, Erik Winfree