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» Comparative genome assembly
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92
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RECOMB
2004
Springer
16 years 26 days ago
Chromosomal breakpoint re-use in the inference of genome sequence rearrangement
In order to apply gene-order rearrangement algorithms to the comparison of genome sequences, Pevzner and Tesler [9] bypass gene finding and ortholog identification, and use the or...
David Sankoff, Phil Trinh
107
Voted
BIBE
2005
IEEE
107views Bioinformatics» more  BIBE 2005»
15 years 6 months ago
DSIM: A Distance-Based Indexing Method for Genomic Sequences
In this paper, we propose a Distance-based Sequence Indexing Method (DSIM) for indexing and searching genome databases. Borrowing the idea of video compression, we compress the ge...
Xia Cao, Beng Chin Ooi, HweeHwa Pang, Kian-Lee Tan...
104
Voted
BMCBI
2006
120views more  BMCBI 2006»
15 years 18 days ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu
117
Voted
BMCBI
2004
115views more  BMCBI 2004»
15 years 13 days ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
119
Voted
RECOMB
2005
Springer
16 years 26 days ago
Individual Gene Cluster Statistics in Noisy Maps
Abstract. Identification of homologous chromosomal regions is important for understanding evolutionary processes that shape genome evolution, such as genome rearrangements and larg...
Narayanan Raghupathy, Dannie Durand