Background: Copy number data are routinely being extracted from genome-wide association study chips using a variety of software. We empirically evaluated and compared four freely-...
Jeanette E. Eckel-Passow, Elizabeth J. Atkinson, S...
A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional method...
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
A number of biological applications require comparison of large genome strings. Current techniques suffer from both disk I/O and computational cost because of extensive memory req...
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...