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106
Voted
CSB
2002
IEEE
121views Bioinformatics» more  CSB 2002»
15 years 5 months ago
Fast and Sensitive Algorithm for Aligning ESTs to Human Genome
There is a pressing need to align growing set of expressed sequence tags (ESTs) to newly sequenced human genome. The problem is, however, complicated by the exon/intron structure ...
Jun Ogasawara, Shinichi Morishita
BMCBI
2007
80views more  BMCBI 2007»
15 years 21 days ago
AT excursion: a new approach to predict replication origins in viral genomes by locating AT-rich regions
Background: Replication origins are considered important sites for understanding the molecular mechanisms involved in DNA replication. Many computational methods have been develop...
David S. H. Chew, Ming-Ying Leung, Kwok Pui Choi
88
Voted
NAR
2007
103views more  NAR 2007»
15 years 3 days ago
InSatDb: a microsatellite database of fully sequenced insect genomes
InSatDb presents an interactive interface to query information regarding microsatellite characteristics per se of five fully sequenced insect genomes (fruitfly, honeybee, malarial...
Sunil Archak, Eshwar Meduri, P. Sravana Kumar, Jav...
83
Voted
RECOMB
2003
Springer
16 years 27 days ago
Designing seeds for similarity search in genomic DNA
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Jeremy Buhler, Uri Keich, Yanni Sun
80
Voted
CSB
2004
IEEE
123views Bioinformatics» more  CSB 2004»
15 years 4 months ago
A New Hardware Architecture for Genomic and Proteomic Sequence Alignment
We describe a novel hardware architecture for genomic and proteomic sequence alignment which achieves a speed-up of two to three orders of magnitude over Smith-Waterman dynamic pr...
Greg Knowles, Paul Gardner-Stephen