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BMCBI
2011
14 years 4 months ago
ENGINES: exploring single nucleotide variation in entire human genomes
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
Jorge Amigo, Antonio Salas, Christopher Phillips
84
Voted
BMCBI
2006
74views more  BMCBI 2006»
15 years 20 days ago
An unsupervised classification scheme for improving predictions of prokaryotic TIS
Background: Although it is not difficult for state-of-the-art gene finders to identify coding regions in prokaryotic genomes, exact prediction of the corresponding translation ini...
Maike Tech, Peter Meinicke
115
Voted
BMCBI
2007
106views more  BMCBI 2007»
15 years 18 days ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
152
Voted
NAR
2007
121views more  NAR 2007»
15 years 3 days ago
WormBase: new content and better access
WormBase (http://wormbase.org), a model organism database for Caenorhabditis elegans and other related nematodes, continues to evolve and expand. Over the past year WormBase has a...
Tamberlyn Bieri, Darin Blasiar, Philip Ozersky, Ig...
139
Voted
GECCO
1999
Springer
130views Optimization» more  GECCO 1999»
15 years 4 months ago
Heterochrony and Adaptation in Developing Neural Networks
This paper discusses the simulation results of a model of biological development for neural networks based on a regulatory genome. The model’s results are analyzed using the fra...
Angelo Cangelosi