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99
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EVOW
2003
Springer
15 years 5 months ago
Chromosomal Breakpoint Detection in Human Cancer
Chromosomal aberrations are differences in DNA sequence copy number of chromosome regions 3 . These differences may be crucial genetic events in the development and progression o...
Kees Jong, Elena Marchiori, Aad van der Vaart, Bau...
99
Voted
NAR
1998
94views more  NAR 1998»
15 years 8 days ago
HuGeMap: a distributed and integrated Human Genome Map database
The HuGeMap database stores the major genetic and physical maps of the human genome. It is also interconnected with the gene radiation hybrid mapping database RHdb. HuGeMap is acc...
Emmanuel Barillot, Frédéric Guyon, C...
108
Voted
RECOMB
2008
Springer
16 years 28 days ago
Perfect DCJ Rearrangement
We study the problem of transforming a multichromosomal genome into another using Double-Cut-and-Join (DCJ) operations. We introduce the notion of DCJ scenario that does not break ...
Sèverine Bérard, Annie Chateau, Cedr...
RECOMB
2006
Springer
16 years 28 days ago
Inferring Gene Orders from Gene Maps Using the Breakpoint Distance
Abstract. Preliminary to most comparative genomics studies is the annotation of chromosomes as ordered sequences of genes. Unfortunately, different genetic mapping techniques usual...
Guillaume Blin, Eric Blais, Pierre Guillon, Mathie...
80
Voted
BMCBI
2006
75views more  BMCBI 2006»
15 years 20 days ago
Improving the specificity of high-throughput ortholog prediction
Background: Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative g...
Debra L. Fulton, Yvonne Y. Li, Matthew R. Laird, B...