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» Comparative mapping of sequence-based and structure-based pr...
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BMCBI
2008
87views more  BMCBI 2008»
14 years 9 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
ISMB
1998
14 years 11 months ago
A Hidden Markov Model for Predicting Transmembrane Helices in Protein Sequences
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
BIBE
2003
IEEE
183views Bioinformatics» more  BIBE 2003»
15 years 2 months ago
Effective Indexing and Filtering for Similarity Search in Large Biosequence Databases
We present a multi-dimensional indexing approach for fast sequence similarity search in DNA and protein databases. In particular, we propose effective transformations of subsequen...
Ozgur Ozturk, Hakan Ferhatosmanoglu