31324 search results - page 6158 / 6265 » Compare |
165
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BMCBI
2011
15 years 5 days ago
2011
Background: We present a novel method to encode ambiguously aligned regions in fixed multiple sequence alignments by ‘Pairwise Identity and Cost Scores Ordination’ (PICS-Ord)....
172
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BMCBI
2011
15 years 5 days ago
2011
Background: High-throughput screening (HTS) is a key part of the drug discovery process during which thousands of chemical compounds are screened and their activity levels measure...
214
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BMCBI
2011
15 years 5 days ago
2011
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
199
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BMCBI
2011
15 years 5 days ago
2011
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
170
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BMCBI
2011
15 years 5 days ago
2011
Background: DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understandin...