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IJAR
2008
93views more  IJAR 2008»
15 years 25 days ago
Prototype based fuzzy classification in clinical proteomics
Proteomic profiling based on mass spectrometry is an important tool for studies at the protein and peptide level in medicine and health care. Thereby, the identification of releva...
Frank-Michael Schleif, Thomas Villmann, Barbara Ha...
JCC
2008
166views more  JCC 2008»
15 years 24 days ago
Reference energy extremal optimization: A stochastic search algorithm applied to computational protein design
: We adapt a combinatorial optimization algorithm, extremal optimization (EO), for the search problem in computational protein design. This algorithm takes advantage of the knowled...
Naigong Zhang, Chen Zeng
106
Voted
ICS
2005
Tsinghua U.
15 years 6 months ago
Lightweight reference affinity analysis
Previous studies have shown that array regrouping and structure splitting significantly improve data locality. The most effective technique relies on profiling every access to eve...
Xipeng Shen, Yaoqing Gao, Chen Ding, Roch Archamba...
147
Voted
ISMB
2008
15 years 3 months ago
Classification of arrayCGH data using fused SVM
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Franck Rapaport, Emmanuel Barillot, Jean-Philippe ...
80
Voted
BMCBI
2007
88views more  BMCBI 2007»
15 years 28 days ago
Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
John P. Rasmussen, Christopher P. Saint, Paul T. M...