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HICSS
2010
IEEE
225views Biometrics» more  HICSS 2010»
15 years 10 months ago
A Comparative Analysis of Professional Forums in the United States Army and Hybrid Communities of Practice in the Civilian Secto
Communities of practice (COPs) have been around since the founding of the first social networks many millennia ago. Organizations around the world over the last two decades have l...
Jon Brickey, Steven Walczak
APAL
2010
97views more  APAL 2010»
15 years 3 months ago
A modal logic framework for reasoning about comparative distances and topology
We propose and investigate a uniform modal logic framework for reasoning about topology and relative distance in metric and more general distance spaces, thus enabling the compari...
Mikhail Sheremet, Frank Wolter, Michael Zakharyasc...
BMCBI
2008
123views more  BMCBI 2008»
15 years 3 months ago
PocketMatch: A new algorithm to compare binding sites in protein structures
Background: Recognizing similarities and deriving relationships among protein molecules is a fundamental requirement in present-day biology. Similarities can be present at various...
Kalidas Yeturu, Nagasuma Chandra
BMCBI
2007
130views more  BMCBI 2007»
15 years 3 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2008
84views more  BMCBI 2008»
15 years 3 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....