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117
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BMCBI
2006
143views more  BMCBI 2006»
15 years 21 days ago
Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
Eric D. Scheeff, Philip E. Bourne
ISSTA
2009
ACM
15 years 7 months ago
A comparative study of programmer-written and automatically inferred contracts
Where do contracts — specification elements embedded in executable code — come from? To produce them, should we rely on the programmers, on automatic tools, or some combinati...
Nadia Polikarpova, Ilinca Ciupa, Bertrand Meyer
95
Voted
EICS
2009
ACM
15 years 4 months ago
A formal approach supporting the comparative predictive assessment of the interruption-tolerance of interactive systems
This paper presents an approach for investigating in a predictive way potential disruptive effects of interruptions on task performance in a multitasking environment. The approach...
Philippe A. Palanque, Marco Winckler, Jean-Fran&cc...
108
Voted
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
15 years 23 days ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
89
Voted
BMCBI
2007
115views more  BMCBI 2007»
15 years 23 days ago
Comparing sequences without using alignments: application to HIV/SIV subtyping
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...