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BMCBI
2010
185views more  BMCBI 2010»
14 years 9 months ago
MetaPIGA v2.0: maximum likelihood large phylogeny estimation using the metapopulation genetic algorithm and other stochastic heu
Background: The development, in the last decade, of stochastic heuristics implemented in robust application softwares has made large phylogeny inference a key step in most compara...
Raphaël Helaers, Michel C. Milinkovitch
BMCBI
2011
14 years 9 months ago
NClassG+: A classifier for non-classically secreted Gram-positive bacterial proteins
Background: Most predictive methods currently available for the identification of protein secretion mechanisms have focused on classically secreted proteins. In fact, only two met...
Daniel Restrepo-Montoya, Camilo Pino, Luis F. Ni&n...
171
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BMCBI
2011
14 years 9 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
121
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BMCBI
2011
14 years 9 months ago
MRCQuant- an accurate LC/MS relative isotopic quantification algorithm on TOF instruments
Background: Relative isotope abundance quantification, which can be used for peptide identification and differential peptide quantification, plays an important role in liquid chro...
William H. Haskins, Konstantinos Petritis, Jianqiu...
122
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BMCBI
2011
14 years 9 months ago
Meta-analysis of gene expression microarrays with missing replicates
Background: Many different microarray experiments are publicly available today. It is natural to ask whether different experiments for the same phenotypic conditions can be combin...
Fan Shi, Gad Abraham, Christopher Leckie, Izhak Ha...