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RECOMB
2009
Springer
15 years 9 months ago
Reconstructing Histories of Complex Gene Clusters on a Phylogeny
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
Tomás Vinar, Brona Brejová, Giltae S...
ICASSP
2007
IEEE
15 years 9 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
BMCBI
2006
92views more  BMCBI 2006»
15 years 2 months ago
Recrafting the neighbor-joining method
Background: The neighbor-joining method by Saitou and Nei is a widely used method for constructing phylogenetic trees. The formulation of the method gives rise to a canonical (n3)...
Thomas Mailund, Gerth Stølting Brodal, Rolf...
BMCBI
2008
133views more  BMCBI 2008»
15 years 2 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
GECCO
2007
Springer
192views Optimization» more  GECCO 2007»
15 years 9 months ago
Estimation of fitness landscape contours in EAs
Evolutionary algorithms applied in real domain should profit from information about the local fitness function curvature. This paper presents an initial study of an evolutionary...
Petr Posík, Vojtech Franc