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BMCBI
2007
88views more  BMCBI 2007»
13 years 6 months ago
Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
John P. Rasmussen, Christopher P. Saint, Paul T. M...
ICCBR
2003
Springer
13 years 11 months ago
Predicting Software Development Project Outcomes
Case-based reasoning is a flexible methodology to manage software development related tasks. However, when the reasoner’s task is prediction, there are a number of different CBR ...
Rosina Weber, Michael Waller, June M. Verner, Will...
BMCBI
2005
82views more  BMCBI 2005»
13 years 6 months ago
A novel method for prokaryotic promoter prediction based on DNA stability
Background: In the post-genomic era, correct gene prediction has become one of the biggest challenges in genome annotation. Improved promoter prediction methods can be one step to...
Aditi Kanhere, Manju Bansal
BMCBI
2011
12 years 9 months ago
Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Holger Pillmann, Klas Hatje, Florian Odronitz, Bjo...
BMCBI
2005
104views more  BMCBI 2005»
13 years 6 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...