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» Comparing transformation methods for DNA microarray data
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BMCBI
2008
108views more  BMCBI 2008»
15 years 2 months ago
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
Background: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications...
David A. Nix, Samir J. Courdy, Kenneth M. Boucher
BMCBI
2011
14 years 5 months ago
Wavelet-based identification of DNA focal genomic aberrations from single nucleotide polymorphism arrays
Background: Copy number aberrations (CNAs) are an important molecular signature in cancer initiation, development, and progression. However, these aberrations span a wide range of...
Youngmi Hur, Hyunju Lee
115
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IDA
2005
Springer
15 years 7 months ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
BMCBI
2004
77views more  BMCBI 2004»
15 years 1 months ago
Graphical technique for identifying a monotonic variance stabilizing transformation for absolute gene intensity signals
Background: The usefulness of log2 transformation for cDNA microarray data has led to its widespread application to Affymetrix data. For Affymetrix data, where absolute intensitie...
Kellie J. Archer, Catherine I. Dumur, Viswanathan ...
CSB
2002
IEEE
221views Bioinformatics» more  CSB 2002»
15 years 7 months ago
DNA Sequence Compression Using the Burrows-Wheeler Transform
-- We investigate off-line dictionary oriented approaches to DNA sequence compression, based on the Burrows-Wheeler Transform (BWT). The preponderance of short repeating patterns i...
Donald A. Adjeroh, Yong Zhang, Amar Mukherjee, Mat...