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117
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BMCBI
2007
15 years 2 months ago
2007
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
129
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BMCBI
2007
15 years 2 months ago
2007
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...
BMCBI
2006
15 years 2 months ago
2006
Background: Normalization of gene expression microarrays carrying thousands of genes is based on assumptions that do not hold for diagnostic microarrays carrying only few genes. T...
120
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BMCBI
2008
15 years 2 months ago
2008
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
103
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BMCBI
2007
15 years 2 months ago
2007
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...