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» Comparing transformation methods for DNA microarray data
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BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
15 years 2 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
90
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BMCBI
2010
109views more  BMCBI 2010»
15 years 2 months ago
Free energy estimation of short DNA duplex hybridizations
Background: Estimation of DNA duplex hybridization free energy is widely used for predicting cross-hybridizations in DNA computing and microarray experiments. A number of software...
Dan C. Tulpan, Mirela Andronescu, Serge Leger
BMCBI
2010
158views more  BMCBI 2010»
15 years 2 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel
BMCBI
2008
121views more  BMCBI 2008»
15 years 2 months ago
Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
ISBRA
2009
Springer
15 years 9 months ago
Practical Quality Assessment of Microarray Data by Simulation of Differential Gene Expression
There are many methods for assessing the quality of microarray data, but little guidance regarding what to do when defective data is identified. Depending on the scientific questio...
Brian E. Howard, Beate Sick, Steffen Heber