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» Comparing transformation methods for DNA microarray data
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BMCBI
2006
86views more  BMCBI 2006»
15 years 2 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
BMCBI
2006
116views more  BMCBI 2006»
15 years 2 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BIBE
2004
IEEE
160views Bioinformatics» more  BIBE 2004»
15 years 6 months ago
A Time Series Analysis of Microarray Data
As the capture and analysis of single-time-point microarray expression data becomes routine, investigators are turning to time-series expression data to investigate complex gene r...
Selnur Erdal, Ozgur Ozturk, David L. Armbruster, H...
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BMCBI
2011
14 years 9 months ago
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
Background: Illumina’s Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw all...
Matthew E. Ritchie, Ruijie Liu, Benilton Carvalho,...
BMCBI
2006
137views more  BMCBI 2006»
15 years 2 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan