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» Comparison of Centralities for Biological Networks
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BMCBI
2006
202views more  BMCBI 2006»
14 years 9 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...
BMCBI
2010
88views more  BMCBI 2010»
14 years 9 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
GCB
2004
Springer
101views Biometrics» more  GCB 2004»
15 years 2 months ago
Kleene's Theorem and the Solution of Metabolic Carbon Labeling Systems
: Carbon Labeling Systems (CLS) are large equation systems that describe the dynamics of labeled carbon atoms in a metabolic network. The rapid solution of these systems is the alg...
Nicole Isermann, Michael Weitzel, Wolfgang Wiecher...
BMCBI
2010
135views more  BMCBI 2010»
14 years 9 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
BMCBI
2005
120views more  BMCBI 2005»
14 years 9 months ago
SpectralNET - an application for spectral graph analysis and visualization
Background: Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks ...
Joshua J. Forman, Paul A. Clemons, Stuart L. Schre...