Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
Heng Li, Liang Guan, Tao Liu, Yiran Guo, Wei-Mou Z...
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
Derandomization by means of mirrored samples has been recently introduced to enhance the performances of (1, λ) and (1 + 2) Evolution-Strategies (ESs) with the aim of designing f...
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...