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RECOMB
2003
Springer
14 years 6 months ago
Physical network models and multi-source data integration
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Chen-Hsiang Yeang, Tommi Jaakkola
BMCBI
2004
150views more  BMCBI 2004»
13 years 6 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
BMCBI
2008
111views more  BMCBI 2008»
13 years 6 months ago
A perl package and an alignment tool for phylogenetic networks
Background: Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of evolutionary events acting at the population level, like recombin...
Gabriel Cardona, Francesc Rosselló, Gabriel...
RECOMB
2004
Springer
14 years 6 months ago
Modeling and Analysis of Heterogeneous Regulation in Biological Networks
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...
Irit Gat-Viks, Amos Tanay, Ron Shamir
NIPS
2008
13 years 7 months ago
Mixed Membership Stochastic Blockmodels
Consider data consisting of pairwise measurements, such as presence or absence of links between pairs of objects. These data arise, for instance, in the analysis of protein intera...
Edoardo Airoldi, David M. Blei, Stephen E. Fienber...