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BMCBI
2007
168views more  BMCBI 2007»
13 years 6 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
ICASSP
2007
IEEE
14 years 21 days ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
BMCBI
2008
164views more  BMCBI 2008»
13 years 6 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2010
160views more  BMCBI 2010»
13 years 1 months ago
eHive: An Artificial Intelligence workflow system for genomic analysis
Background: The Ensembl project produces updates to its comparative genomics resources with each of its several releases per year. During each release cycle approximately two week...
Jessica Severin, Kathryn Beal, Albert J. Vilella, ...
PVLDB
2010
129views more  PVLDB 2010»
13 years 4 months ago
iGraph: A Framework for Comparisons of Disk-Based Graph Indexing Techniques
Graphs are of growing importance in modeling complex structures such as chemical compounds, proteins, images, and program dependence. Given a query graph Q, the subgraph isomorphi...
Wook-Shin Han, Jinsoo Lee, Minh-Duc Pham, Jeffrey ...