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BIOINFORMATICS
2011
14 years 4 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
BMCBI
2011
14 years 4 months ago
R2R - software to speed the depiction of aesthetic consensus RNA secondary structures
Background: With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these mol...
Zasha Weinberg, Ronald R. Breaker
BMCBI
2011
14 years 4 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
BMCBI
2011
14 years 4 months ago
CODA (CrossOver Distribution Analyzer): quantitative characterization of crossover position patterns along chromosomes
Background: During meiosis, homologous chromosomes exchange segments via the formation of crossovers. This phenomenon is highly regulated; in particular, crossovers are distribute...
Franck Gauthier, Olivier C. Martin, Matthieu Falqu...
BMCBI
2011
14 years 4 months ago
pROC: an open-source package for R and S+ to analyze and compare ROC curves
Background: Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often r...
Xavier Robin, Natacha Turck, Alexandre Hainard, Na...
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