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AC
1998
Springer
15 years 4 months ago
Cellular Automata Models of Self-Replicating Systems
Abstract: Since von Neumann's seminal work around 1950, computer scientists and others have studied the algorithms needed to support self-replicating systems. Much of this wor...
James A. Reggia, Hui-Hsien Chou, Jason D. Lohn
BMCBI
2011
14 years 11 months ago
Hierarchical graphs for rule-based modeling of biochemical systems
Background: In rule-based modeling, graphs are used to represent molecules: a colored vertex represents a component of a molecule, a vertex attribute represents the internal state...
Nathan W. Lemons, Bin Hu, William S. Hlavacek
VLSID
1998
IEEE
116views VLSI» more  VLSID 1998»
15 years 8 months ago
Synthesis of Testable RTL Designs
With several commercial tools becoming available, the high-level synthesis of applicationspeci c integrated circuits is nding wide spread acceptance in VLSI industry today. Existi...
C. P. Ravikumar, Sumit Gupta, Akshay Jajoo
BMCBI
2010
105views more  BMCBI 2010»
15 years 4 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
AAAI
1994
15 years 5 months ago
Knowledge Refinement in a Reflective Architecture
A knowledge acquisition tool should provide a user with maximum guidance in extending and debugging a knowledge base, by preventing inconsistencies and knowledge gaps that may ari...
Yolanda Gil