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108
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BMCBI
2010
208views more  BMCBI 2010»
15 years 22 days ago
Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene
Background: Image analysis is an essential component in many biological experiments that study gene expression, cell cycle progression, and protein localization. A protocol for tr...
Zafer Aydin, John I. Murray, Robert H. Waterston, ...
130
Voted
BMCBI
2010
202views more  BMCBI 2010»
15 years 22 days ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
91
Voted
BMCBI
2007
112views more  BMCBI 2007»
15 years 22 days ago
Integrated olfactory receptor and microarray gene expression databases
Background: Gene expression patterns of olfactory receptors (ORs) are an important component of the signal encoding mechanism in the olfactory system since they determine the inte...
Nian Liu, Chiquito J. Crasto, Minghong Ma
BMCBI
2010
124views more  BMCBI 2010»
15 years 22 days ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
115
Voted
BMCBI
2008
170views more  BMCBI 2008»
15 years 22 days ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou