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ALMOB
2007
111views more  ALMOB 2007»
15 years 5 months ago
Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12
Motivation: Transcriptional regulatory network (TRN) discovery from one method (e.g. microarray analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack ...
Jingjun Sun, Kagan Tuncay, Alaa Abi Haidar, Lisa E...
ALMOB
2007
133views more  ALMOB 2007»
15 years 5 months ago
Characteristics of predictor sets found using differential prioritization
Background: Feature selection plays an undeniably important role in classification problems involving high dimensional datasets such as microarray datasets. For filter-based featu...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng
BMCBI
2010
178views more  BMCBI 2010»
15 years 5 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2010
148views more  BMCBI 2010»
15 years 5 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
BMCBI
2010
105views more  BMCBI 2010»
15 years 5 months ago
GWAMA: software for genome-wide association meta-analysis
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...
Reedik Mägi, Andrew P. Morris
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