Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp
Current domain-specific modeling (DSM) frameworks for designing component-based systems often consider the system's structural and behavioral concerns as the two dominant con...
Sumant Tambe, Akshay Dabholkar, Aniruddha S. Gokha...
We consider two-player games played over finite state spaces for an infinite number of rounds. At each state, the players simultaneously choose moves; the moves determine a succ...
Luca de Alfaro, Rupak Majumdar, Vishwanath Raman, ...
Background: Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from ...
Eva Grafahrend-Belau, Falk Schreiber, Monika Heine...
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...