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BMCBI
2008
127views more  BMCBI 2008»
15 years 4 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
144
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BMCBI
2008
128views more  BMCBI 2008»
15 years 4 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
151
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BMCBI
2008
153views more  BMCBI 2008»
15 years 4 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
BMCBI
2008
242views more  BMCBI 2008»
15 years 4 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
BMCBI
2010
104views more  BMCBI 2010»
15 years 4 months ago
FragViz: visualization of fragmented networks
Background: Researchers in systems biology use network visualization to summarize the results of their analysis. Such networks often include unconnected components, which popular ...
Miha Stajdohar, Minca Mramor, Blaz Zupan, Janez De...
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