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BMCBI
2008
127views more  BMCBI 2008»
14 years 10 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2006
111views more  BMCBI 2006»
14 years 10 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
KDD
2005
ACM
130views Data Mining» more  KDD 2005»
15 years 10 months ago
Simple and effective visual models for gene expression cancer diagnostics
In the paper we show that diagnostic classes in cancer gene expression data sets, which most often include thousands of features (genes), may be effectively separated with simple ...
Gregor Leban, Minca Mramor, Ivan Bratko, Blaz Zupa...
BMCBI
2007
106views more  BMCBI 2007»
14 years 10 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
RECOMB
2011
Springer
14 years 25 days ago
Algorithms for MDC-Based Multi-locus Phylogeny Inference
One of the criteria for inferring a species tree from a collection of gene trees, when gene tree incongruence is assumed to be due to incomplete lineage sorting (ILS), is minimize ...
Yun Yu, Tandy Warnow, Luay Nakhleh