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» Computation in Gene Networks
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CCE
2008
14 years 10 months ago
Informative gene selection and design of regulatory networks using integer optimization
A central problem in bioinformatics and systems biology is the selection of appropriate models in a rational and systematic way. This fundamentally combinatorial problem can be re...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Ioa...
BMCBI
2007
90views more  BMCBI 2007»
14 years 10 months ago
Gene network interconnectedness and the generalized topological overlap measure
Background: Network methods are increasingly used to represent the interactions of genes and/ or proteins. Genes or proteins that are directly linked may have a similar biological...
Andy M. Yip, Steve Horvath
ISMDA
2001
Springer
15 years 2 months ago
Web-Enabled Knowledge-Based Analysis of Genetic Data
We present a web-based implementation of GenePath, an intelligent assistant tool for data analysis in functional genomics. GenePath considers mutant data and uses expert-defined pa...
Peter Juvan, Blaz Zupan, Janez Demsar, Ivan Bratko...
CEC
2008
IEEE
15 years 4 months ago
Toward a gene regulatory network model for evolving chemotaxis behavior
— Inspired from bacteria, a gene regulatory network model for signal transduction is presented in this paper. After describing experiments on stabilizing the population size for ...
Neale Samways, Yaochu Jin, Xin Yao, Bernhard Sendh...
BMCBI
2010
152views more  BMCBI 2010»
14 years 10 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...