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» Computation in Gene Networks
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BIOCOMP
2006
14 years 11 months ago
The Generalized Topological Overlap Matrix for Detecting Modules in Gene Networks
Systems biologic studies of gene and protein interaction networks have found that these networks are comprised of `modules' (groups of tightly interconnected nodes). Module i...
Andy M. Yip, Steve Horvath
ACMSE
2006
ACM
15 years 4 months ago
Automatic quality assessment of Affymetrix GeneChip data
Computing reliable gene expression levels from microarray experiments is a sophisticated process with many potential pitfalls. Quality control is one of the most important steps i...
Steffen Heber, Beate Sick
BMCBI
2004
205views more  BMCBI 2004»
14 years 10 months ago
A combinational feature selection and ensemble neural network method for classification of gene expression data
Background: Microarray experiments are becoming a powerful tool for clinical diagnosis, as they have the potential to discover gene expression patterns that are characteristic for...
Bing Liu, Qinghua Cui, Tianzi Jiang, Songde Ma
BMCBI
2007
168views more  BMCBI 2007»
14 years 10 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
BMCBI
2008
166views more  BMCBI 2008»
14 years 10 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf