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BMCBI
2010
114views more  BMCBI 2010»
14 years 10 months ago
Detection of gene orthology from gene co-expression and protein interaction networks
Background: Ortholog detection methods present a powerful approach for finding genes that participate in similar biological processes across different organisms, extending our und...
Fadi Towfic, Susan VanderPlas, Casey A. Oliver, Ol...
BMCBI
2007
182views more  BMCBI 2007»
14 years 9 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2002
128views more  BMCBI 2002»
14 years 9 months ago
Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in euka
Background: Gene regulation in eukaryotes is mainly effected through transcription factors binding to rather short recognition motifs generally located upstream of the coding regi...
Michele Caselle, Ferdinando Di Cunto, Paolo Prover...
BMCBI
2006
82views more  BMCBI 2006»
14 years 10 months ago
A method for computing the overall statistical significance of a treatment effect among a group of genes
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
Robert R. Delongchamp, Taewon Lee, Cruz Velasco
RECOMB
2005
Springer
15 years 3 months ago
An Interactive Map of Regulatory Networks of Pseudomonas aeruginosa Genome
For studying gene regulatory and protein signaling networks, we have developed an interactive map for the Pseudomonas aeruginosa genome. We first represent genes, proteins and the...
Weihui Wu, Yongling Song, Shouguang Jin, Su-Shing ...