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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
14 years 10 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
ICPR
2004
IEEE
15 years 11 months ago
Feature Selection and Gene Clustering from Gene Expression Data
In this article we describe an algorithm for feature selection and gene clustering from high dimensional gene expression data. The method is based on measuring similarity between ...
D. Dutta Majumder, Pabitra Mitra
BMCBI
2010
116views more  BMCBI 2010»
14 years 10 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...
BMCBI
2010
172views more  BMCBI 2010»
14 years 10 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
JCP
2006
157views more  JCP 2006»
14 years 9 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...