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ICPR
2008
IEEE
15 years 4 months ago
A fuzzy c-means algorithm using a correlation metrics and gene ontology
A fuzzy c-means algorithm was adapted for analyzing microarray data. The adaptation consisted of initialization of fuzzy centroids using gene ontology information and the use of P...
Mingrui Zhang, Terry M. Therneau, Michael A. McKen...
CIBCB
2005
IEEE
15 years 3 months ago
Heuristic Algorithm for Computing Reversal Distance with MultiGene Families via Binary Integer Programming
— Hannenhalli and Pevzner developed the first polynomial-time algorithm for the combinatorial problem of sorting of signed genomic data. Their algorithm solves the minimum numbe...
Jakkarin Suksawatchon, Chidchanok Lursinsap, Mikae...
RECOMB
2010
Springer
14 years 8 months ago
An Approximation Algorithm for Computing a Parsimonious First Speciation in the Gene Duplication Model
We consider the following problem: given a forest of gene family trees on a set of genomes, find a first speciation which splits these genomes into two subsets and minimizes the ...
Aïda Ouangraoua, Krister M. Swenson, Cedric C...
ICPPW
2005
IEEE
15 years 3 months ago
Gene Sequence Alignment on a Public Computing Platform
Public computing can potentially supply not only computational power but also memory and short term storage resources to grid and cluster scale problems. Gene sequence alignment i...
Stephen Pellicer, Nova Ahmed, Yi Pan, Yao Zheng
ISDA
2006
IEEE
15 years 3 months ago
From Gene to Drug: A Proof of Concept for a Plausible Computational Pathway
The last decade has witnessed an exponential growth of sequence information in the field of biological macromolecules such as proteins and nucleic acids and their interactions wit...
Sandhya Shenoy, B. Jayaram, N. Latha, Pooja Narang...