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» Computation of Homology Groups and Generators
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TPDS
1998
112views more  TPDS 1998»
14 years 11 months ago
Parallel Computation in Biological Sequence Analysis
—A massive volume of biological sequence data is available in over 36 different databases worldwide, including the sequence data generated by the Human Genome project. These data...
Tieng K. Yap, Ophir Frieder, Robert L. Martino
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
14 years 11 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
BMCBI
2006
143views more  BMCBI 2006»
14 years 11 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
IJDMB
2008
128views more  IJDMB 2008»
14 years 11 months ago
Protein homology detection with biologically inspired features and interpretable statistical models
: Computational classification of proteins using methods such as string kernels and Fisher-SVM has demonstrated great success. However, the resulting models do not offer an immedia...
Pai-Hsi Huang, Vladimir Pavlovic
BMCBI
2006
180views more  BMCBI 2006»
14 years 11 months ago
Building multiclass classifiers for remote homology detection and fold recognition
Motivation Protein remote homology prediction and fold recognition are central problems in computational biology. Supervised learning algorithms based on support vector machines a...
Huzefa Rangwala, George Karypis