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» Computation of Median Gene Clusters
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BMCBI
2005
89views more  BMCBI 2005»
14 years 9 months ago
Theme discovery from gene lists for identification and viewing of multiple functional groups
Background: High throughput methods of the genome era produce vast amounts of data in the form of gene lists. These lists are large and difficult to interpret without advanced com...
Petri Pehkonen, Garry Wong, Petri Töröne...
BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong
BIBE
2010
IEEE
181views Bioinformatics» more  BIBE 2010»
14 years 10 months ago
Multi Level Clustering of Phylogenetic Profiles
The prediction of gene function from genome sequences is one of the main issues in Bioinformatics. Most computational approaches are based on the similarity between sequences to in...
Fotis E. Psomopoulos, Pericles A. Mitkas
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RECOMB
2005
Springer
15 years 10 months ago
The Incompatible Desiderata of Gene Cluster Properties
Abstract. There is widespread interest in comparative genomics in determining if historically and/or functionally related genes are spatially clustered in the genome, and whether t...
Rose Hoberman, Dannie Durand
BMCBI
2010
214views more  BMCBI 2010»
14 years 9 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper