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» Computational Challenges of Systems Biology
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JIB
2007
95views more  JIB 2007»
14 years 11 months ago
Integration of constraints documented in SBML, SBO, and the SBML Manual facilitates validation of biological models
The creation of quantitative, simulatable, Systems Biology Markup Language (SBML) models that accurately simulate the system under study is a time-intensive manual process that re...
Allyson L. Lister, Matthew R. Pocock, Anil Wipat
CODASPY
2011
14 years 3 months ago
The challenge of data and application security and privacy (DASPY): are we up to it
This talk gives a personal perspective on the topic area of this new conference on data and application security and privacy, the difficult nature of the challenge we are confron...
Ravi S. Sandhu
BMCBI
2008
115views more  BMCBI 2008»
14 years 12 months ago
BioGraphE: high-performance bionetwork analysis using the Biological Graph Environment
Background: Graphs and networks are common analysis representations for biological systems. Many traditional graph algorithms such as k-clique, k-coloring, and subgraph matching h...
George Chin Jr., Daniel G. Chavarría-Mirand...
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GCB
2009
Springer
154views Biometrics» more  GCB 2009»
15 years 3 months ago
Comparative Identification of Differential Interactions from Trajectories of Dynamic Biological Networks
Abstract: It is often challenging to reconstruct accurately a complete dynamic biological network due to the scarcity of data collected in cost-effective experiments. This paper ad...
Zhengyu Ouyang, Mingzhou Song
RECOMB
2005
Springer
16 years 4 days ago
Decomposition of Overlapping Protein Complexes: A Graph Theoretical Method for Analyzing Static and Dynamic Protein Associations
Background: Most cellular processes are carried out by multi-protein complexes, groups of proteins that bind together to perform a specific task. Some proteins form stable complex...
Elena Zotenko, Katia S. Guimarães, Raja Jot...