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BMCBI
2008
149views more  BMCBI 2008»
14 years 12 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
ICCAD
2005
IEEE
79views Hardware» more  ICCAD 2005»
15 years 8 months ago
The impact of the nanoscale on computing systems
— Nanoscale technologies provide both challenges and opportunities. We show that the issues and potential solutions facing designers are technology independent and arise mainly f...
Seth Copen Goldstein
DAC
2007
ACM
16 years 26 days ago
Multi-Core Design Automation Challenges
The trend to multi-core chip designs presents new challenges for design automation, while the increased reuse of components may offer solutions. This paper describes some of the k...
John A. Darringer
BIB
2007
53views more  BIB 2007»
14 years 12 months ago
Current Progress in computational metabolomics
Being a relatively new addition to the ‘omics’ field, metabolomics is still evolving its own computational infrastructure and assessing its own computational needs. Due to its...
David S. Wishart
CMSB
2009
Springer
15 years 6 months ago
Modelling Biological Clocks with Bio-PEPA: Stochasticity and Robustness for the Neurospora crassa Circadian Network
Circadian clocks are biochemical networks, present in nearly all living organisms, whose function is to regulate the expression of specific mRNAs and proteins to synchronise rhyth...
Ozgur E. Akman, Federica Ciocchetta, Andrea Degasp...