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» Computational Heuristics for Simplifying a Biological Model
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87
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ASM
2010
ASM
15 years 6 months ago
Reasoned Modelling Critics: Turning Failed Proofs into Modelling Guidance
The activities of formal modelling and reasoning are closely related. But while the rigour of building formal models brings significant benefits, formal reasoning remains a major...
Andrew Ireland, Gudmund Grov, Michael Butler
JCSS
2007
116views more  JCSS 2007»
14 years 9 months ago
The most probable annotation problem in HMMs and its application to bioinformatics
Hidden Markov models (HMMs) are often used for biological sequence annotation. Each sequence feature is represented by a collection of states with the same label. In annotating a ...
Brona Brejová, Daniel G. Brown 0001, Tom&aa...
RECOMB
1997
Springer
15 years 1 months ago
Sequence alignment with tandem duplication
Algorithm development for comparing and aligning biological sequences has, until recently, been based on the SI model of mutational events which assumes that modi cation of sequen...
Gary Benson
86
Voted
RECOMB
2005
Springer
15 years 9 months ago
Pairwise Local Alignment of Protein Interaction Networks Guided by Models of Evolution
Abstract. With ever increasing amount of available data on protein-protein interaction (PPI) networks and research revealing that these networks evolve at a modular level, discover...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...
RECOMB
2007
Springer
15 years 9 months ago
A Bayesian Model That Links Microarray mRNA Measurements to Mass Spectrometry Protein Measurements
Abstract. An important problem in biology is to understand correspondences between mRNA microarray levels and mass spectrometry peptide counts. Recently, a compendium of mRNA expre...
Anitha Kannan, Andrew Emili, Brendan J. Frey