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    BMCBI
    2010
    105views more  BMCBI 2010»
    A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
    14 years 9 months ago
    A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
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    Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
    Tiejun Cheng, Zhihai Liu, Renxiao Wang
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    FUZZIEEE
    2007
    IEEE
    151views Fuzzy Logic» more  FUZZIEEE 2007»
    Mining and Predicting CpG islands
    15 years 3 months ago
    Mining and Predicting CpG islands
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    — A DNA sequence can be described as a string composed of four symbols: A, T, C and G. Each symbol represents a chemically distinct nucleotide molecule. Combinations of two nucle...
    Christopher Previti, Oscar Harari, Coral del Val
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    BMCBI
    2004
    208views more  BMCBI 2004»
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
    14 years 9 months ago
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
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    Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
    Vadim Alexandrov, Mark Gerstein
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    BMCBI
    2007
    124views more  BMCBI 2007»
    Analysis on multi-domain cooperation for predicting protein-protein interactions
    14 years 9 months ago
    Analysis on multi-domain cooperation for predicting protein-protein interactions
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    Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
    Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
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    RTSS
    2008
    IEEE
    166views Control Systems» more  RTSS 2008»
    Predictable Interrupt Management and Scheduling in the Composite Component-Based System
    15 years 3 months ago
    Predictable Interrupt Management and Scheduling in the Composite Component-Based System
    Download  www.seas.gwu.edu
    This paper presents the design of user-level scheduling hierarchies in the Composite component-based system. The motivation for this is centered around the design of a system that...
    Gabriel Parmer, Richard West
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