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JCB
2002
131views more  JCB 2002»
14 years 11 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
BMCBI
2007
146views more  BMCBI 2007»
14 years 12 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2005
86views more  BMCBI 2005»
14 years 11 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
BMCBI
2010
115views more  BMCBI 2010»
14 years 12 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2005
119views more  BMCBI 2005»
14 years 11 months ago
Proceedings of the Second Annual Conference of the MidSouth Computational Biology and Bioinformatics Society
The MCBIOS 2004 conference brought together regional researchers and students in biology, computer science and bioinformatics on October 7th-9th 2004 to present their latest work....
Jonathan D. Wren, William Slikker Jr.