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NAR
2010
94views more  NAR 2010»
14 years 6 months ago
Saccharomyces Genome Database provides mutant phenotype data
The Saccharomyces Genome Database (SGD; http:// www.yeastgenome.org) is a scientific database for the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which i...
Stacia R. Engel, Rama Balakrishnan, Gail Binkley, ...
STOC
1995
ACM
194views Algorithms» more  STOC 1995»
15 years 3 months ago
Transforming cabbage into turnip: polynomial algorithm for sorting signed permutations by reversals
Genomes frequently evolve by reversals ␳(i, j) that transform a gene order ␲1 . . . ␲i␲iϩ1 . . . ␲jϪ1␲j . . . ␲n into ␲1 . . . ␲i␲jϪ1 . . . ␲iϩ1␲j . . ....
Sridhar Hannenhalli, Pavel A. Pevzner
BMCBI
2006
203views more  BMCBI 2006»
14 years 12 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
CPM
2004
Springer
107views Combinatorics» more  CPM 2004»
15 years 3 months ago
Sorting by Reversals in Subquadratic Time
The problem of sorting a signed permutation by reversals is inspired by genome rearrangements in computational molecular biology. Given two genomes represented as two signed permut...
Eric Tannier, Marie-France Sagot
JCB
2008
90views more  JCB 2008»
14 years 11 months ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah