Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
Ivan Borozan, Limin Chen, Bryan Paeper, Jenny E. H...
A binary matrix has the Consecutive Ones Property (C1P) if its columns can be ordered in such a way that all 1s on each row are consecutive. Algorithmic issues of the C1P are centr...
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Background: Several mathematical and statistical methods have been proposed in the last few years to analyze microarray data. Most of those methods involve complicated formulas, a...
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...