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BMCBI
2008
125views more  BMCBI 2008»
14 years 12 months ago
MAID : An effect size based model for microarray data integration across laboratories and platforms
Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
Ivan Borozan, Limin Chen, Bryan Paeper, Jenny E. H...
CIE
2010
Springer
15 years 3 months ago
A Faster Algorithm for Finding Minimum Tucker Submatrices
A binary matrix has the Consecutive Ones Property (C1P) if its columns can be ordered in such a way that all 1s on each row are consecutive. Algorithmic issues of the C1P are centr...
Guillaume Blin, Romeo Rizzi, Stéphane Viale...
BMCBI
2010
214views more  BMCBI 2010»
14 years 12 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2007
185views more  BMCBI 2007»
14 years 12 months ago
GEDI: a user-friendly toolbox for analysis of large-scale gene expression data
Background: Several mathematical and statistical methods have been proposed in the last few years to analyze microarray data. Most of those methods involve complicated formulas, a...
André Fujita, João Ricardo Sato, Car...
BMCBI
2006
110views more  BMCBI 2006»
14 years 12 months ago
Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...