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RECOMB
2007
Springer
15 years 6 months ago
Network Legos: Building Blocks of Cellular Wiring Diagrams
Publicly-available data sets provide detailed and large-scale information on multiple types of molecular interaction networks in a number of model organisms. These multi-modal univ...
T. M. Murali, Corban G. Rivera
BMCBI
2011
14 years 3 months ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
14 years 12 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
RECOMB
2005
Springer
16 years 4 days ago
Modeling the Combinatorial Functions of Multiple Transcription Factors
A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...
Chen-Hsiang Yeang, Tommi Jaakkola
BMCBI
2007
168views more  BMCBI 2007»
14 years 12 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...