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105
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BMCBI
2006
127views more  BMCBI 2006»
14 years 11 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
RECOMB
2002
Springer
15 years 12 months ago
String barcoding: uncovering optimal virus signatures
There are many critical situations when one needs to rapidly identify an unidentified pathogen from among a given set of previously sequenced pathogens. DNA or RNA hybridization c...
Sam Rash, Dan Gusfield
98
Voted
BMCBI
2008
147views more  BMCBI 2008»
14 years 11 months ago
Simple integrative preprocessing preserves what is shared in data sources
Background: Bioinformatics data analysis toolbox needs general-purpose, fast and easily interpretable preprocessing tools that perform data integration during exploratory data ana...
Abhishek Tripathi, Arto Klami, Samuel Kaski
106
Voted
BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...
BMCBI
2007
131views more  BMCBI 2007»
14 years 11 months ago
ISHAPE: new rapid and accurate software for haplotyping
Background: We have developed a new haplotyping program based on the combination of an iterative multiallelic EM algorithm (IEM), bootstrap resampling and a pseudo Gibbs sampler. ...
Olivier Delaneau, Cédric Coulonges, Pierre-...