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» Computational analysis and learning for a biologically motiv...
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EVOW
2010
Springer
14 years 1 months ago
Grammatical Evolution Decision Trees for Detecting Gene-Gene Interactions
DEODHAR, SUSHAMNA DEODHAR. Using Grammatical Evolution Decision Trees for Detecting Gene-Gene Interactions in Genetic Epidemiology. (Under the direction of Dr. Alison Motsinger-Re...
Sushamna Deodhar, Alison A. Motsinger-Reif
ISMB
2004
13 years 7 months ago
Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 6 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2007
138views more  BMCBI 2007»
13 years 6 months ago
A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic
Background: A key challenge in metabonomics is to uncover quantitative associations between multidimensional spectroscopic data and biochemical measures used for disease risk asse...
Aki Vehtari, Ville-Petteri Mäkinen, Pasi Soin...
CEC
2010
IEEE
13 years 7 months ago
Evolutionary layered hypernetworks for identifying microRNA-mRNA regulatory modules
Abstract-- Exploring microRNA (miRNA) and mRNA regulatory interactions may give new insights into diverse biological phenomena. While elucidating complex miRNA-mRNA interactions ha...
Soo-Jin Kim, JungWoo Ha, Bado Lee, Byoung-Tak Zhan...